HYPERFOCUSTM
HYPERFOCUSTM drives computational and empirical identification of druggable targets prioritized by SPOTLIGHTTM and validated by cryo-EM.
Computational modeling without structural validation can
lead to compound design dead-ends. HYPERFOCUSTM combines real
experimental data with fragment libraries and virtual screening to refine and
confirm our predictions.
HYPERFOCUSTM enables us to create detailed
structural models of potential drug pockets and show where candidate compounds
bind to proteins, offering valuable insight into how these compounds affect
protein structures and interactions.
HYPERFOCUSTM leverages computational predictions
against cryo-EM data to generate a comprehensive picture of how binding affects
protein structures and their interactions beyond what is possible with
conventional computational methods alone.