CRYO-CADD TM

CRYO-CADDTM powers Gandeeva’s drug discovery engine through a rapid iterative cycle that generates structural insights.

CRYO-CADDTM enables rapid hit-to-lead optimization. In this process, chemical scaffolds are optimized via iterative structure-guided design, a cycle we repeat until we optimize a development candidate.

By using high-throughput cryo-EM to generate the structures that guide the CRYO-CADDTM cycle, Gandeeva is shortening the timeline from hit to experimental leads.

A more precise hit-to-lead process eliminates off-target binding, leading to rationally designed on-target therapeutics without the potential side effects.